RESEARCH
ELiS Teams

UBL-
Uncharted Biosynthetic Landscapes
We are interested in discovering novel bioactive microbial metabolites. Microbial metabolites play important roles in medicine and they are a key source of antibiotics, anticancer agents or immunosuppressants. We develop sequencing, bioinformatics and synthetic biology methods to rapidly detect and characterize novel genes responsible for the biosynthesis of cryptic microbial metabolites. We also work on involving the general public in helping to source new…

SynBAI-
Synthetic Biology and Artificial Intelligence
The Pandi team research focuses on the development of de novo antimicrobial peptides via a combined approach of machine learning and synthetic biology. Additionally, we use machine learning models to predict and design phase-separating polypeptides and build codon and gene expression language models.

SEED-
Systems Engineering and Evolution Dynamics
The Lindner team’s main efforts rely on years of investment in building an intellectual and experimental framework based on interdisciplinary approaches, harnessing physics and computer science and on welcoming young researchers to address key questions in Life Sciences with Systems and Synthetic Biology approaches, mainly focusing on Escherichia coli as the simplest model organism. Focal projects include study of phenotypic variability, ageing…
ELiS Hosted Start-Ups
ELiS iGEM Team

The main concept of our project is to develop a bio-manufacturable lubricant gel which binds to target proteins on pathogen surfaces, thus immobilizing them and acting as a physical barrier for infection and transmission. The binding protein, its target, and consequently the target pathogen will be highly modular through AI-based protein design using RF Diffusion.
iGEM (International Genetically Engineered Machine) competition is a worldwide synthetic biology competition that was initially aimed at improving people’s understanding of synthetic biology while also developing an open community and collaboration between groups composed of university students, but also high school students, entrepreneurs, overgraduates…